Functional analyses have identified human-origin commensal bacteria that promote tolerant responses in the immune system that prevent or can reverse food allergies. Our team has identified specific strains and their mechanisms of action that promote these effects. We have developed two protective consortia and a third that promotes the development of allergic responses. This third consortium is providing biomarkers and further mechanistic understanding of the dysbiosis that contributes to the development of food allergies.
- Gut-Protect I: Defined flora with treat-to-prevent and treat-to-cure activities, obligately anaerobic consortium with no tolerance for the presence of oxygen
- Gut-Protect II: Defined flora with treat-to-prevent activities and better tolerance to the presence of oxygen.
- Negative Control Consortium (NCC): Defined species that skew the immune system from tolerance to allergy.